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Pharmacist Shares Insight on Zinc Interactions

November 5, 2025

Insight from Associate Professor of Clinical Specialties Maria Pino, Ph.D., is featured in a  article about supplements and medications that can interact with zinc. Pino, a licensed New York State pharmacist, details zinc’s possible interactions with antibiotics, noting that the mineral can interfere with quinolone antibiotics (like Cipro), which are used to treat a wide range of bacterial infections, including urinary tract infections. The same is true for tetracyclines, a class of antibiotics commonly prescribed to treat acne and other infections.

“Zinc would decrease the efficacy of the antibiotic,� Pino said. “It wouldn’t cause true harm, but it would not make the drug effective, and that could lead to [patients] not getting better.�

She also notes that these interactions are a two-way street, with antibiotics potentially impairing the body’s ability to absorb zinc, too.